{"id":87443,"date":"2023-08-01T16:16:06","date_gmt":"2023-08-01T08:16:06","guid":{"rendered":"http:\/\/www.broadbio.com\/?p=87443"},"modified":"2023-08-01T16:16:09","modified_gmt":"2023-08-01T08:16:09","slug":"nrc%e6%a0%87%e5%87%86%e5%93%81%e8%b4%bb%e8%b4%9d%e7%bb%84%e7%bb%87crm-psp-mus%e7%a8%b3%e5%ae%9a%e6%80%a7","status":"publish","type":"post","link":"http:\/\/www.broadbio.com\/archives\/87443","title":{"rendered":"NRC\u6807\u51c6\u54c1\u8d3b\u8d1d\u7ec4\u7ec7CRM-PSP-Mus\u7a33\u5b9a\u6027"},"content":{"rendered":"\n<p><strong>\u5206\u6790\u65b9\u6cd5\u4e0e\u4ef7\u503c\u5206\u914d<\/strong><\/p>\n\n\n\n<p>\u4f7f\u7528\u4e24\u79cd\u5206\u6790\u65b9\u6cd5\u83b7\u5f97STX\u3001GTX2\u548cGTX3\u7684\u8ba4\u8bc1\u503c\u3002CRM PSP\nMus\u63d0\u53d6\u7269\u91c7\u7528\u6539\u826f\u81eaAOAC\u63d0\u53d6\u7a0b\u5e8f[6]\u7684\u6db2-\u56fa\u8403\u53d6\uff08LSE\uff09\u65b9\u6cd5\u5236\u5907\uff088g\u7ec4\u7ec7\uff0c\u4f7f\u75280.1M HCl\u4e09\u6b65\u63d0\u53d6\uff0c\u6700\u7ec8\u4f53\u79ef\u4e3a25ml[2]\uff09\u3002\u4f7f\u7528\u6539\u826f\u7248\u7684LC-pcox FLD\u65b9\u6cd5[7]\uff08\u56fe3\uff09\u548c\u4eb2\u6c34\u76f8\u4e92\u4f5c\u7528\u6db2\u76f8\u8272\u8c31-\u4e32\u8054\u8d28\u8c31\u6cd5\uff08HILIC-MS\/MS\uff09\u8fdb\u884c\u5206\u6790\uff08\u56fe4\uff09\u3002\u5bf9\u4e8eLC pcox FLD\uff0c\u4f7f\u7528STX\u6821\u51c6\u6eb6\u6db2\uff08CRM-STX\u548cCRM-GTX2\u548c3\uff09\u7684\u7cbe\u786e\u7a00\u91ca\u6db2\u8fdb\u884c\u5916\u90e8\u6821\u51c6\u3002\u5bf9\u4e8eHILIC-MS\/MS\uff0c\u4f7f\u7528\u76f8\u540cCRM\u5236\u5907\u7684\u52a0\u6807\u6eb6\u6db2\u8fdb\u884c\u6807\u51c6\u6dfb\u52a0\uff0c\u4ee5\u8865\u507f\u57fa\u8d28\u6548\u5e94\u3002CRM PSP Mus\u7684\u4fe1\u606f\u503c\uff08\u88682\uff09\u4f7f\u7528\u4e00\u79cd\u6216\u4e24\u79cd\u76f8\u540c\u7684\u6280\u672f\u5206\u914d\uff0c\u4f7f\u7528NRC\u6821\u51c6\u6eb6\u6db2\uff08CRM-NEO\u3001CRM dcSTX\u3001CRM-dcGTX2&amp;3\u548cCRM-GTX1&amp;4\uff09\u7684\u7a00\u91ca\u6db2\u4f5c\u4e3a\u6821\u51c6\u54c1\u3002DA\u548cepiDA\u7684\u8ba4\u8bc1\u503c\uff08\u88683\uff09\u662f\u901a\u8fc7\u4f7f\u7528\u7a77\u4e3e\u6db2-\u56fa\u8403\u53d6\u6cd5\uff084\u514b\u7ec4\u7ec7\uff0c50\u6beb\u534750%\u7532\u9187\u6c34\u6eb6\u6db2\uff0c4\u6b65\u7a0b\u5e8f\uff09\u8403\u53d6\u6837\u54c1\u83b7\u5f97\u7684\u3002\u8fc7\u6ee4\u540e\u7684\u63d0\u53d6\u7269\u901a\u8fc7LC-UV\u548cLC-MS\/MS\u8fdb\u884c\u5206\u6790\uff08\u56fe5\uff09\u3002LC-MS\/MS\u4e2d\u672a\u89c2\u5bdf\u5230\u663e\u8457\u7684\u57fa\u8d28\u6548\u5e94\u3002\u4f7f\u7528CRM-DA\u7684\u7cbe\u786e\u7a00\u91ca\u6db2\u8fdb\u884c\u6821\u51c6\u3002\u8ba4\u8bc1\u503c\u7531DA\u53ca\u5176C5\u2019-\u975e\u5bf9\u6620\u5f02\u6784\u4f53\uff0cC5\u2019-epiDA\uff0c\u5176UV\u5149\u8c31\u4e0eDA\u7684UV\u5149\u8c31\u76f8\u540c\u3002LC-UV\u5bf9DA\u548cepiDA\u7684\u5355\u4e2a\u6d53\u5ea6\u7684\u4fe1\u606f\u503c\u5206\u522b\u4e3a30.8\u548c2.8 mg\/kg\u3002\u4f7f\u7528CRM-OA\u4f5c\u4e3a\u6821\u51c6\u54c1\uff0c\u901a\u8fc7LC-MS\/MS\u5728CRM PSP Mus\u4e2d\u6d4b\u91cf\u4f4e\u6d53\u5ea6\u7684\u5188\u7530\u9178\uff08OA\uff09\u3002\u78b1\u6c34\u89e3\u524d\u540eOA\u7684\u4fe1\u606f\u503c\u4e3a\u5206\u522b\u4e3a0.03\u00b5g\/g\u548c0.06\u00b5g\/g\u3002<\/p>\n\n\n\n<p>\u540c\u8d28\u6027<\/p>\n\n\n\n<p><strong>NRC\u6807\u51c6\u54c1\u8d3b\u8d1d\u7ec4\u7ec7CRM-PSP-Mus<\/strong>\u4ee3\u8868\u6027\u6570\u91cf\u7684CRM PSP Mus\u74f6\u5b50\u662f\u4ece\u6574\u4e2a\u704c\u88c5\u7cfb\u5217\u4e2d\u9009\u62e9\u7684\u3002STX\u548cDA\u7684\u76f8\u5bf9\u6d53\u5ea6\u5206\u522b\u901a\u8fc7LC-pcox FLD\u548cLC-UV\u6d4b\u91cf\u3002\u5747\u5300\u6027\u6d4b\u8bd5\u7684\u4e0d\u786e\u5b9a\u6027\u8d21\u732e\u5305\u542b\u5728CRM PSP Mus\u7684\u603b\u4f53\u4e0d\u786e\u5b9a\u6027\u9884\u7b97\u4e2d\uff08\u88684\uff09\u3002<\/p>\n\n\n\n<p>\u7a33\u5b9a\u6027<\/p>\n\n\n\n<p>\u5f53\u50a8\u5b58\u5728-12\u00b0C\u65f6\uff0cSTX\u548cDA\u5728CRM PSP Mus\u4e2d\u8868\u73b0\u51fa\u826f\u597d\u7684\u7a33\u5b9a\u6027\u3002\u7ecf\u8fc7\u8ba4\u8bc1\u7684\u5206\u6790\u7269\u5728+4\u00b0C\u6e29\u5ea6\u4e0b\u4e24\u5468\u5185\u6ca1\u6709\u663e\u8457\u964d\u89e3\u3002<\/p>\n\n\n\n<p>\u5b89\u5168\u8bf4\u660e<\/p>\n\n\n\n<p><strong>NRC\u6807\u51c6\u54c1\u8d3b\u8d1d\u7ec4\u7ec7CRM-PSP-Mus<\/strong>\u542b\u6709STX\u548cDA\uff0c\u8fd9\u4e24\u79cd\u6bd2\u7d20\u5206\u522b\u5bfc\u81f4\u9ebb\u75f9\u6027\u8d1d\u7c7b\u4e2d\u6bd2\u548c\u9057\u5fd8\u6027\u8d1d\u7c7b\u4e2d\u6bd2\u3002\u53ea\u6709\u5408\u683c\u7684\u4eba\u5458\u624d\u80fd\u5904\u7406\u6750\u6599\uff0c\u5e76\u5e94\u4f7f\u7528\u9002\u5f53\u7684\u5904\u7406\u65b9\u6cd5\u3002\u5b89\u5168\u6570\u636e\u8868\uff08SDS\uff09\u53ef\u7528\u4e8eCRM PSP Mus\u3002<\/p>\n\n\n\n<p>\u6709\u6548\u671f<\/p>\n\n\n\n<p>\u5982\u679c\u5728\u5efa\u8bae\u7684-12\u00b0C\u6216\u66f4\u4f4e\u7684\u50a8\u5b58\u6761\u4ef6\u4e0b\u672a\u5f00\u5c01\u50a8\u5b58\uff0c\u5219CRM PSP Mus\u7684\u8ba4\u8bc1\u6d53\u5ea6\u81ea\u9500\u552e\u4e4b\u65e5\u8d77\u6709\u6548\u671f\u4e3a1\u5e74\u3002<\/p>\n\n\n\n<p>\u8ba1\u91cf\u6eaf\u6e90\u6027<\/p>\n\n\n\n<p>\u672c\u8bc1\u4e66\u4e2d\u7684\u7ed3\u679c\u53ef\u901a\u8fc7NRC\u8ba4\u8bc1\u7684STX\uff08CRM-STX-e\uff09\u3001GTX2\u548cGTX3\uff08CRM-GTX2&amp;3-c\uff09\u4ee5\u53caDA\uff08CRM-DA-f\uff09\u53c2\u8003\u6750\u6599\u8ffd\u6eaf\u5230SI\uff08Syst\u00e8me\ninternational d&#8217;unit\u00e9s\uff09\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5206\u6790\u65b9\u6cd5\u4e0e\u4ef7\u503c\u5206\u914d \u4f7f\u7528\u4e24\u79cd\u5206\u6790\u65b9\u6cd5\u83b7\u5f97STX\u3001GTX2\u548cGTX3\u7684\u8ba4\u8bc1\u503c\u3002CRM PSP Mus\u63d0\u53d6\u7269\u91c7\u7528\u6539 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[92],"tags":[],"_links":{"self":[{"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/posts\/87443"}],"collection":[{"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/comments?post=87443"}],"version-history":[{"count":1,"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/posts\/87443\/revisions"}],"predecessor-version":[{"id":87453,"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/posts\/87443\/revisions\/87453"}],"wp:attachment":[{"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/media?parent=87443"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/categories?post=87443"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.broadbio.com\/wp-json\/wp\/v2\/tags?post=87443"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}