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\"\"<\/figure>\n\n\n\n

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DA\u7684\u8ba4\u8bc1\u503c\u662f\u901a\u8fc7\u4f7f\u7528\u5b8c\u5168\u7a77\u5c3d\u7684\u6db2-\u56fa\u8403\u53d6\u6cd5\uff084\u514b\u7ec4\u7ec7\u548c50\u6beb\u534750%\u7532\u9187\u6c34\u6eb6\u6db2\uff0c4\u6b65\u7a0b\u5e8f\uff09\u8403\u53d6\u6837\u54c1\u83b7\u5f97\u7684\u3002\u8fc7\u6ee4\u540e\u7684\u63d0\u53d6\u7269\u901a\u8fc7LC-MS\/MS\u548cLC-UV\u8fdb\u884c\u5206\u6790\uff08\u56fe4\uff09\u3002LC-MS\/MS\u4e2d\u672a\u53d1\u73b0\u663e\u8457\u7684\u57fa\u8d28\u6548\u5e94\u3002\u4f7f\u7528\u7ecf\u8ba4\u8bc1\u7684DA\u6821\u51c6\u6eb6\u6db2\uff08CRM-DA-f\uff09\u7684\u51c6\u786e\u7a00\u91ca\u6db2\u8fdb\u884c\u6821\u51c6\u3002\u8ba4\u8bc1\u503c\u7531DA\u53ca\u5176C5′-\u975e\u5bf9\u6620\u5f02\u6784\u4f53C5′-epiDA\u7684\u7ec4\u5408\u6d53\u5ea6\u7ec4\u6210\uff0c\u5176UV\u5149\u8c31\u4e0eDA\u7684UV\u5149\u8c31\u76f8\u540c\u3002LC-UV\u6cd5\u6d4b\u5b9a\u7684DA\u548cepiDA\u5355\u72ec\u6d53\u5ea6\u7684\u4fe1\u606f\u503c\u5206\u522b\u4e3a11.5\u548c0.3 mg\/kg\uff08\u88684\uff09\u3002<\/p>\n\n\n\n

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